اشتر JWH-018 عبر الإنترنت

ما هو JWH-018؟

JWH-018 (1-pentyl-3-(1-naphthoyl)indole, NA-PIMO[3] or AM-678) is a naphthoylindole-based analgesic that functions as a full agonist at both the CB1 and CB2 cannabinoid receptors, with modest selectivity for CB2. It has effects in animals that are comparable to those of tetrahydrocannabinol (THC), a cannabinoid found naturally in cannabis, which has led to its use in synthetic cannabis products sold legally in some countries as “incense blends”.

اشتر JWH-018 عبر الإنترنت

Buy JWH-018, Our online store in USA sells JWH 018 powder. We offer several versions of the herbal mixture “Spice”. Due to the intoxicating properties of this synthetic cannabinoid, which are similar to those of 9-THC in cannabis, it is mostly consumed illegally. While jwh 018 is significantly more effective than similar cannabis dosages, it also presents significant challenges in identification using traditional 9-THC testing methods. In July 2009, JWH-018 was added to the U.S. Drug Enforcement Administration’s (DEA) list of drugs and chemicals of concern . In addition to reports of Spice seizures in Ohio and Florida, other states, including Alabama, Arkansas and Florida, have passed laws restricting the sale or possession of JWH-018 powder .

JWH-018 للبيع | اطلب JWH-018 عبر الإنترنت

يتم تحضير JWH 018، وهو ناهض انتقائي معتدل لمستقبلات القنب الطرفية (CB2)، من أميني ألكيليندول WIN 55,212-2. تبلغ قيم Ki للارتباط بمستقبلات CB1 وCB2 9.0 و2.94 نانومتر، على التوالي، لنسبة CB1:CB2 تبلغ 3.061. تم اختبار الفئران وكانت النتائج مماثلة لنتائج WIN 55,212-2 من حيث درجة حرارة المستقيم، وأقصى تأثير مضاد للألم في اختبار نفض الذيل وتثبيط النشاط التلقائي. بيع مسحوق JWH 018 عبر الإنترنت في الولايات المتحدة الأمريكية. Narco Powders.

JWH-018 متوفر في أوروبا

According to animal pharmacological studies, the pill JWH-018 has a similar effect to 9-THC. In mice it causes analgesia, a drop in body temperature, catalepsy and a general decrease in activity. By combining these four effects, scientists can predict psychoactivity in humans comparable to that of 9-THC. JWH-018’s performance in all four tests suggests that it is likely to produce psychoactive effects in humans comparable to those of THC. In drug discrimination studies in rats, JWH-018 generalized to 9-THC and elicited subjective responses similar to those of 9-THC. JWH-018 binds to the cannabinoid receptor CB1 in the brain with greater affinity than 9-THC and exhibits agonistic properties in functional assays, suggesting that it may act similarly to 9-THC in vivo .

اشتر القنب الصناعي

على عكس التتراهيدروكانابينول THC، وهو ناهض غير مكتمل في مستقبلات CB1، فإن شراء JWH-018 عبر الإنترنت والعديد من أشباه القنب المُعدلة هندسياً هي ناهضات كاملة. وقد ثبت أن التتراهيدروكانابينول يعيق النقل العصبي لمستقبلات GABA في المخ من خلال عدة مسارات. يمكن أن يسبب JWH-018 توعكًا شديدًا وقشعريرة وفي حالات نادرة (معظمها لدى عملاء JWH غير القياسيين) نوبات صرع لأنه يثبط النقل العصبي GABA بشكل أكثر كفاية من THC. يمكن أن تشكل الناهضات الكاملة لمستقبلات القنب مخاطر حقيقية على العميل إذا تم استخدامها بشكل مفرط.

Various physical and mental unfriendly effects have been noted while using JWH-018 purchased online. In one study, insane relapses and malaise were described as side effects in thoroughly treated patients with mental illnesses after inhaling JWH-018.[21] Due to concerns about the ability of JWH-018 and other manufactured cannabinoids to cause psychosis in vulnerable people, it has been suggested that individuals with risk factors for insanity (such as a past or family history of psychosis) should not use these substances.