JWH-018をオンラインで購入する

JWH-018とは？

JWH-018 (1-pentyl-3-(1-naphthoyl)indole, NA-PIMO[3] or AM-678) is a naphthoylindole-based analgesic that functions as a full agonist at both the CB1 and CB2 cannabinoid receptors, with modest selectivity for CB2. It has effects in animals that are comparable to those of tetrahydrocannabinol (THC), a cannabinoid found naturally in cannabis, which has led to its use in synthetic cannabis products sold legally in some countries as “incense blends”.

JWH-018をオンラインで購入する

Buy JWH-018, Our online store in USA sells JWH 018 powder. We offer several versions of the herbal mixture “Spice”. Due to the intoxicating properties of this synthetic cannabinoid, which are similar to those of 9-THC in cannabis, it is mostly consumed illegally. While jwh 018 is significantly more effective than similar cannabis dosages, it also presents significant challenges in identification using traditional 9-THC testing methods. In July 2009, JWH-018 was added to the U.S. Drug Enforcement Administration’s (DEA) list of drugs and chemicals of concern . In addition to reports of Spice seizures in Ohio and Florida, other states, including Alabama, Arkansas and Florida, have passed laws restricting the sale or possession of JWH-018 powder .

JWH-018の販売｜JWH-018をオンラインで注文する

JWH 018は、アミノアルキルインドールWIN 55,212-2から調製された末梢性カンナビノイド(CB2)受容体の中程度の選択的アゴニストである。CB1およびCB2受容体への結合Ki値はそれぞれ9.0および2.94 nMであり、CB1:CB2比は3.061であった。ラットを用いた試験の結果、直腸温、テールフリックアッセイにおける最大抗侵害受容作用、自発活動の抑制という点で、WIN 55,212-2と同等の結果が得られた。JWH 018 粉末を米国でオンライン販売。 Narco Powders.

JWH-018は欧州で入手可能

According to animal pharmacological studies, the pill JWH-018 has a similar effect to 9-THC. In mice it causes analgesia, a drop in body temperature, catalepsy and a general decrease in activity. By combining these four effects, scientists can predict psychoactivity in humans comparable to that of 9-THC. JWH-018’s performance in all four tests suggests that it is likely to produce psychoactive effects in humans comparable to those of THC. In drug discrimination studies in rats, JWH-018 generalized to 9-THC and elicited subjective responses similar to those of 9-THC. JWH-018 binds to the cannabinoid receptor CB1 in the brain with greater affinity than 9-THC and exhibits agonistic properties in functional assays, suggesting that it may act similarly to 9-THC in vivo .

合成カンナビノイドの購入

CB1受容体において不完全な作動薬であるTHCとは異なり、JWH-018のオンライン購入や多くの人工カンナビノイドは完全な作動薬である。THCは、いくつかの経路を通じて大脳のGABA受容体の神経伝達を阻害することが示されている。JWH-018は、THCよりも適切にGABA神経伝達を阻害するため、極度の倦怠感、悪寒、まれに（主にJWHの非標準的な顧客において）発作を引き起こすことがある。カンナビノイド受容体フルアゴニストは、過剰に使用された場合、顧客に現実的な危険をもたらす可能性がある。

Various physical and mental unfriendly effects have been noted while using JWH-018 purchased online. In one study, insane relapses and malaise were described as side effects in thoroughly treated patients with mental illnesses after inhaling JWH-018.[21] Due to concerns about the ability of JWH-018 and other manufactured cannabinoids to cause psychosis in vulnerable people, it has been suggested that individuals with risk factors for insanity (such as a past or family history of psychosis) should not use these substances.